Process for preparing optically-active 4-amino-3-hydroxybutyric

Details Process for preparing optically-active 4-amino-3-hydroxybutyric Process for preparing optically-active 4-amino-3-hydroxybutyric

1984-01-23

1986-04-22

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing nitrogen-containing organic compound

435146, 435280, 435822, 435830, 435843, 435863, 562567, 558410, C12P 1300, C12R 101, C07C10130, C07C119042

Patent

active

045842701

ABSTRACT:
The present invention relates to processes for preparing optically-active 4-amino-3-hydroxybutyric acid by asymmetrically cleaving one of the enantiotopic ester groupings of 3-hydroxyglutaric diester by the action of microbial enzymes to obtain a chiral monoacid which is readily converted into optically-active 4-amino-3-hydroxybutyric acid by chemical means.

REFERENCES:
patent: 3823069 (1974-07-01), Miyaki
patent: 4371618 (1983-02-01), Cavazza

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