Process for preparing optically active 2,3-dihydrobenzofuran...

Details Process for preparing optically active 2,3-dihydrobenzofuran... Process for preparing optically active 2,3-dihydrobenzofuran...

2005-04-12

2005-04-12

Owens, Amelia A. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

06878831

ABSTRACT:
A process for preparing optically active 2,3-dihydrobenzofuran compounds which comprises subjecting a 2,3-dihydrobenzofuran compound represented by the general formula or a salt thereof to optical resolution with an optically active acid compound:[wherein R1and R2are each hydrogen or an optionally substituted hydrocarbon group; R3is an optionally substituted aromatic group; and C is a benzene ring which may further have a substituent in addition to the amino group]. The process enables industrially advantageous production of intermediates for the synthesis of optically active 2,3-dihydrobenzofuran compounds useful as preventive and/or therapeutic drugs for neurodegenerative diseases and so on.

REFERENCES:
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patent: 180276 (1986-05-01), None
patent: 1136477 (2001-09-01), None
patent: WO 0034262 (2000-06-01), None
patent: WO 0130763 (2001-05-01), None

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