Process for preparing of non-thrombogenic substrates

Details Process for preparing of non-thrombogenic substrates Process for preparing of non-thrombogenic substrates

1990-09-27

1991-12-10

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

514 54, 514 56, 530395, 424486, 424488, 536 41, 536123, 536124, 523112, A61K 31715, A61K 3702

Patent

active

050719734

ABSTRACT:
The present invention refers to a method concerning the preparation of hemo-compatible substrates by incorporation, adhesion and/or modification and embodiment of non-thrombogenic endothelial cell surface polysaccharide (HS I) in its peptide-bound or free form on and/or mixed with synthetic and biopolymers (Substrates) by way of physical distribution, adhesion to the surface and/or chemical embodiment, which can be used in medicine as blood-compatible substrates. These polymers can be presented in form of fibres, hollow fibres, membranes, organ spare parts, canulas, syringes, tubes, blood containers, or in other forms, or they can be prepared from other material.

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