Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrate esters or chalcogen analogues thereof
Reexamination Certificate
2007-04-03
2007-04-03
Powers, Fiona T. (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrate esters or chalcogen analogues thereof
Reexamination Certificate
active
10523722
ABSTRACT:
The present invention refers to a process for preparing a compound of general formula (A), as reported in the description, wherein R is a radical of naproxen or bromonaproxen and R1–R12are hydrogen or alkyl groups, m, n, o, q, r and s are each independently an integer from 0 to 6, and p is 0 or 1, and and X is O, S, SO, SO2, NR13or PR13 or an aryl, heteroaryl group, said process comprising reacting a compound of formula (B)in-line-formulae description="In-line Formulae" end="lead"?R—COOZ (B)in-line-formulae description="In-line Formulae" end="tail"?wherein R is as defined above and Z is hydrogen or a cation selected from: Li+, Na+, K+, Ca++, Mg++, tetralkylammonium, tetralkylphosphonium, with a compound of formula (C), as reported in the description, wherein R1–R12 and m, n, o, p, q, r, s are as defined above and Y is a suitable leaving group.
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Benedini Francesca
Del Soldato Piero
Santus Giancarlo
Arent & Fox LLP
Nicox S.A.
Powers Fiona T.
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