Process for preparing nicotinamide adenine dinucleotide...

Details Process for preparing nicotinamide adenine dinucleotide... Process for preparing nicotinamide adenine dinucleotide...

2011-01-04

2011-01-04

Swope, Sheridan (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Reexamination Certificate

active

07863014

ABSTRACT:
The present invention provides a novel process for preparing nicotinamide adenine dinucleotide phosphate (NADP). The process of the present invention comprises performing phosphorylation using a polyphosphoric acid or a salt thereof and nicotinamide adenine dinucleotide (NAD+) as substrates in the presence of a polyphosphate-dependent NAD+kinase from aMycobacterium, wherein the reaction solution contains 0.1-15% by weight of the polyphosphoric acid or a salt thereof, and 5-150 mM of a divalent metal ion.

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