Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1978-03-08
1979-08-07
Rotman, Alan L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D23114
Patent
active
041638581
ABSTRACT:
New imidazolemethylphosphonium salts having a degradable group at the 2-position which are useful intermediates for preparing histamine H.sub.2 antagonists. This invention concerns the preparation of imidazolemethylphosphonium salts having no substituent at the 2-position by heating the compounds referred to above.
REFERENCES:
patent: 2844582 (1958-07-01), Raley
patent: 3185699 (1965-05-01), Sherlock
Hofmann Imidazole and its Derivatives Part I, pp. 175-178, N.Y., Interscience, 1953.
Labaw Clifford S.
Webb Robert L.
Wellman George R.
Edgerton William H.
Rotman Alan L.
SK&F Lab Co.
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