Process for preparing neotrehalose and its uses

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435 99, 53612313, 536124, C12P 1912, C12P 1914, C13K 1300

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054037271

ABSTRACT:
Neotrehalose is prepared in a relatively high-yield by a process comprising allowing .beta.-galactosidase to act on a solution containing lactoneotrehalose to form neotrehalose and recovering the resultant neotrehalose. The neotrehalose is a non-reducing oligosaccharide having a satisfiable stability and a rich- and high-quality-sweetness and is assimilated and utilized as energy source in vivo when orally administered. Neotrehalose in the form of crystal has a satisfiable handleability because it is readily soluble in water and substantially free of hygroscopicity. These render neotrehalose very useful in the fields of food-, cosmetic- and pharmaceutical-industries.

REFERENCES:
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Sharp et al., J. Chem. Society, pp. 258-288 (1951).
Onishi et al., Chemical Abstracts, vol. 76(21), #127294y (1970).
W. M. Haworth et al. Synthesis of New Disaccharide Neotrehalose, Journal of the Chemical Society, pp. 2847-2850 (1931).
V. E. Sharp et al. Synthesis of Trehalose-Type Disaccharides, Journal of the Chemical Society, pp. 258-288 (1951).
K. Matsuda, Studies on the Disaccharides in Koji Extract and Sake. Journal of the Agricultural Chemical Society of Japan, vol. 30, No. 2, pp. 119-123 (1959).
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J. Howard Bradbury et al. Determination of the Structures of Trisaccharides by . . . Spectroscopy. Carbohydrate Research, pp. 125-156 (1984).

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