Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1995-06-05
1998-06-16
Kulkosky, Peter F.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
528491, 528493, A61K 914, A61K 951
Patent
active
057666350
ABSTRACT:
Nanoparticles are prepared by dissolving a poly(ethylene oxide) and/or poly(propylene oxide) polylactic copolymer in an organic solvent followed by formation of nanoparticles by mixing the solution containing the polymer with an aqueous solution and by precipitation, without using an additional colloidal protective agent or by microfluidization and solvent evaporation. Nanoparticles prepared by this method are disclosed.
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Bazile Didier
Michalon Jean-Paul
Prud'Homme Christian
Spenleuhauer Gilles
Veillard Michel
Kulkosky Peter F.
Oehler Ross J.
Rhone-Poulenc Rorer S.A.
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