Process for preparing N-tert-butyl-2-pyrazinecarboxamide and N-t

Details Process for preparing N-tert-butyl-2-pyrazinecarboxamide and N-t Process for preparing N-tert-butyl-2-pyrazinecarboxamide and N-t

1998-01-20

1999-07-13

Bernhardt, Emily

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544406, C07D24104

Patent

active

059228733

ABSTRACT:
A process for preparing a N-tert-butyl-2-pyrazinecarboxamide having the formula (2): ##STR1## which comprises reacting a cyanopyrazine having the formula (1): ##STR2## with tert-butyl alcohol in the presence of sulfuric acid and a process for preparing a N-tert-butyl-2-piperazine-carboxamide having the formula (3): ##STR3## which comprises hydrogenating of said N-tert-butyl-2-pyrazinecarboxamide having the formula (2) in the presence of Raney nickel or Raney cobalt.

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