Process for preparing N-substituted histidine derivatives

Details Process for preparing N-substituted histidine derivatives Process for preparing N-substituted histidine derivatives

1988-09-16

1990-06-26

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548342, C07D23364

Patent

active

049373528

ABSTRACT:
A process is disclosed for the preparation of new N.sup..tau. -substituted histidine derivatives of the general formula ##STR1## According to the process, a histidine derivative of the general formula ##STR2## is reacted with phosgene, and the resultant product is then alkylated and thereafter hydrolyzed with an acid.
The products obtained by the process are highly useful for prepration of histidine-analogous proteins and enzymes.

REFERENCES:
patent: 4734276 (1988-03-01), Ziegler

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