Process for preparing N-carbamoyl-D-thienylglycines

Details Process for preparing N-carbamoyl-D-thienylglycines Process for preparing N-carbamoyl-D-thienylglycines

1979-03-09

1980-12-30

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

435106, 435280, 435828, 435832, 435840, 435843, 435863, 435874, 435826, 435872, 435886, C12P 1700

Patent

active

042424526

ABSTRACT:
A process for preparing N-carbamoyl-D-(2-thienyl or 3-thienyl)glycine by subjecting 5-(2-thienyl or 3-thienyl)hydantoin to the action of a cultured broth, cells or treated cells of microorganisms having an ability of stereospecifically hydrolyzing the hydantoin ring. N-carbamoyl-D-(2-thienyl or 3-thienyl)glycine is a useful intermediate for the preparation of medicines and can be readily converted into D-(2-thienyl or 3-thienyl)glycine.

REFERENCES:
patent: 3198804 (1965-08-01), Johnson et al.
patent: 4065353 (1977-12-01), Cecere et al.
patent: 4094741 (1978-06-01), Yamada et al.
Nishimura et al., J. Chem. Soc. Japan, vol. 82, No. 12, 1688-1691 (1961).

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