Process for preparing methyl 4-(aminomethyl)benzoate

Details Process for preparing methyl 4-(aminomethyl)benzoate Process for preparing methyl 4-(aminomethyl)benzoate

2007-09-04

2007-09-04

Witherspoon, Sikarl A. (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C560S098000, C560S129000

Reexamination Certificate

active

11525279

ABSTRACT:
An advantageous process is provided for preparing methyl 4-(aminomethyl)benzoate by esterifying 4-(aminomethyl)benzoic acid and subsequently obtaining the methyl 4-(aminomethyl)benzoate, this process proceeding under specific pH and temperature control and isolation of the hydrochloride of methyl 4-(aminomethyl)benzoate formed as an intermediate being avoidable.

REFERENCES:
patent: 6172084 (2001-01-01), Cuny et al.
patent: 1972-0075050 (1974-03-01), None
patent: 1973-0136140 (1975-07-01), None
patent: 1977-0104929 (1979-04-01), None
patent: 1979-0085926 (1981-02-01), None
patent: 1989-4670483 (1991-07-01), None
Umino, Norihide, et al., “Sodium Acyloxyborohydride as New Reducing Agents. II. Reduction of Nitriles to the corresponding Amines”;Tetrahedron LettersNo. 33, pp. 2875-2876, (1976).
Heinzman, Stephen W., et al., “The Mechanism of Sodium Borohydride-Cobaltous Chloride Reductions”;J. Am. Chem. Soc.1982, 104, pp. 6801-6802.
Suzuki, Hitomi, et al., “A Chemoselective Conversion of Alkyl and Aryl Azides to Amines with Sodium Hydrogentelluride”,Chemistry Letters1984, p. 1733.
Takamizawa, Satoshi, et al., “Supported Nickel-Catalyzed Hydrogenation of Aromatic Nitriles under Low Pressure Conditions”,Synlett 2001, No. 10, p. 1623.

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