Process for preparing m-phenoxybenzylalcohol and side-chain halo

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260613R, C07C 4100

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active

040149404

ABSTRACT:
A process for preparing m-phenoxybenzyl, m-phenoxybenzal halides or a mixture thereof comprising halogenating m-phenoxytoluene in the presence of a phosphorus halide in the high temperature region above 220.degree. C, and a process for preparing m-phenoxybenzylalcohol comprising halogenating m-phenoxytoluene as above, reacting the resulting side-chain halogenated m-phenoxytoluene with an alkali metal salt of acetic acid and then (a) reducing and hydrolyzing the resulting m-phenoxybenzylacetate and m-phenoxybenzaldehyde, or (b) reducing the resulting m-phenoxybenzylacetate and m-phenoxybenzaldehyde, reacting the resulting product with acetic anhydride and an alkali metal salt of acetic acid and hydrolyzing the resulting m-phenoxybenzylacetate are disclosed.

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patent: 3280199 (1966-10-01), Schmerling
patent: 3859364 (1975-01-01), Wilson
Wagner et al., Synthetic Org. Chem., (1953) 484.

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