Process for preparing lysergol derivatives

Details Process for preparing lysergol derivatives Process for preparing lysergol derivatives

1979-04-03

1980-11-04

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D45702

Patent

active

042321573

ABSTRACT:
A novel process is disclosed for the preparation of derivatives of lysergol having the general formula: ##STR1## According to this process lysergol is directly used as the starting compound and, after the methylation at the 1 position of the corresponding 10 alpha-methoxy-lumilysergol, the methylated compound is directly esterified with a carboxylic acid R--COOH, the acid being selected in the group comprising aliphatic, cycloaliphatic, aromatic, and heterocyclic carboxylic acids, containing up to 10 carbon atoms.

REFERENCES:
patent: 3228943 (1966-01-01), Bernardi et al.
patent: 3879554 (1975-04-01), Temperilli et al.
patent: 3966739 (1976-06-01), Bernardi et al.

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