Process for preparing lincomycin derivatives

Details Process for preparing lincomycin derivatives Process for preparing lincomycin derivatives

1976-01-30

1977-06-21

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 4, C07H 1516

Patent

active

040313042

ABSTRACT:
Alkyl 7-deoxy-7-.omega.-substituted alkylthio-.alpha.-thiolincos-aminides useful as intermediates for preparing anti-bacterially active 7-deoxy-7-.omega.-substituted alkylthiolincomycins are prepared by heating alkyl N-acyl-6,7-aziridino-6-deamino-7-deoxy-.alpha.-thiolincosaminides with an appropriate thiol in the presence of an anhydrous lower hydrocarbon carboxylic acid.

REFERENCES:
patent: 3689474 (1972-09-01), Kagan et al.
patent: 3767649 (1973-10-01), Bannister
patent: 3790560 (1974-02-01), Bannister

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