Process for preparing lincomycin and clindamycin ribonucleotides

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 162, 536 164, 536 165, 536 28, 536 29, C07H 1516

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active

044304951

ABSTRACT:
Novel and useful ribonucleotides of analogs of the well known antibiotics lincomycin and clindamycin. These ribonucleotides are unexpectedly highly active against Streptococcus hemolyticus and Staphylococcus aureus in vivo. These ribonucleotides are prepared by using resting cell or cell-free extracts of Streptomyces rochei, NRRL 3533, or cell-free extracts of Streptomyces coelicolor, NRRL 3532.

REFERENCES:
patent: 3671647 (1972-06-01), Argoudelis et al.
patent: 4278789 (1981-07-01), Birkenmeyer
patent: 4310660 (1982-01-01), Birkenmeyer
patent: 4383109 (1983-05-01), Argoudelis et al.

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