Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1996-08-15
1998-10-20
Killos, Paul J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C07C 6966
Patent
active
058248188
ABSTRACT:
A process for preparing a lactate which includes: (a) preparing lactonitrile from prussic acid and acetaldehyde, (b) hydrating the lactonitrile to form lactamide, (c) forming the desired lactate and formamide from lactamide and formate (or methanol and carbon monoxide), (d) separating and collecting components, having a lower boiling point than that of lactate from the reaction liquid in step (c), by distillation under specified conditions, and (e) dehydrating formamide from step (d) to form prussic acid and recycling the prussic acid to step (a). Heretofore, lactates had been manufactured by forming lactonitrile (cyanohydrin) from acetaldehyde and prussic acid, and then esterifying lactonitrile with a mineral acid or the like. However, in this conventional process, ammonium salts were formed as by-products in an amount equal to that of the lactate. According to the present invention, a lactate can be efficiently manufactured on a commercial scale without forming a large amount of the ammonium salts as by-products. In particular, the yield of the lactate can be increased by controlling the formation of 2-formyloxy propionate and also a dimer of a lactate.
REFERENCES:
patent: 1682347 (1928-08-01), Matheson et al.
patent: 1790262 (1931-01-01), Christmann
patent: 2041820 (1936-05-01), Crawford
patent: 3567749 (1971-03-01), Neugebauer et al.
patent: 4983757 (1991-01-01), Ishikawa et al.
patent: 4990651 (1991-02-01), Ikarashi et al.
patent: 5225594 (1993-07-01), Shima et al.
Patent Abstracts of Japan, vol. 7, No. 143 (C-172) (1288) 22 Jun. 1983 of JP-A-58 055 444 (Mitsubishi Gas Kagaku K.K.), 1 Apr. 1983.
Patent Abstracts of Japan, vol. 14, No. 68 (C-0686) 8 Feb. 1990 of JP-A-01 290 653 (Mitsubishi Gas Chem. Co., Inc.) 22 Nov. 1989.
Abe Takafumi
Gotoh Toshiyuki
Higuchi Hirofumi
Ikemoto Kazuto
Shima Yoshikazu
Killos Paul J.
Mitsubishi Gas Chemical Company Inc.
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