Process for preparing L-malic acid

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435180, 435182, 435840, 435843, 435849, 435873, 435938, C12P 746

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active

044865325

ABSTRACT:
At least one acryl or allyl monomer is polymerized in an aqueous suspension containing a fumarase-producing microorganism. The resultant immobilized fumarase-producing microorganism is contacted with bile acids or salts thereof. Then, the immobilized fumarase-producing microorganism is subjected to enzymatic reaction with fumaric acid or a salt thereof. L-Malic acid is prepared without the production of the by-product succinic acid.

REFERENCES:
patent: 2972566 (1961-02-01), Kitahara
patent: 3063910 (1962-11-01), Abe et al.
patent: 3922195 (1975-11-01), Chibata et al.
patent: 3980520 (1976-09-01), Degen et al.
Dixon et al, "Enzymes" Academic Press 1964, pp. 32-35, 387-389, 548-549 and 634-635.
Rose et al, "The Condensed Chemical Dictionary", Van Nostrand Reinhold Co. 1970, p. 118.

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