Process for preparing L-aspartic acid

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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C12P 1322

Patent

active

059522062

ABSTRACT:
An improved process for preparing L-aspartic acid by enzyme-catalyzed reaction of fumaric acid with ammonia, in which, after reaction has been completed, excess ammonia is removed from the reaction mixture, L-aspartic acid is precipitated by adding acetic acid or formic acid, whereupon formic acid and acetic acid are rereleased from the mother liquor by adding fumaric acid, and the ammonia released and the liberated formic or acetic acid and the ammonium fumarate formed in the liberation are reused for subsequent cycles.

REFERENCES:
patent: 4326029 (1982-04-01), Yukawa et al.
patent: 4560653 (1985-12-01), Sherwin et al.
patent: 4692409 (1987-09-01), Kisumi et al.
patent: 5541090 (1996-07-01), Sakano et al.
patent: 5741681 (1998-04-01), Kato et al.

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