Process for preparing isothiocyanato functionalized metal comple

Organic compounds -- part of the class 532-570 series – Organic compounds – Radioactive metal containing

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534 11, 534 14, 534 15, 424 11, 424 8591, 556136, 556137, 560347, C07F 1500, C07C26310, A61K 4300

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active

050066439

ABSTRACT:
The present invention is directed to a novel process for preparing isothiocyanate functionalized chelates by reacting amino functionalized chelates with thiophosgene.

REFERENCES:
patent: 4454106 (1984-06-01), Gansow et al.
patent: 4885363 (1989-12-01), Tweedle et al.
March, J. Advanced Organic Chemistry, 3d ed., (John Wiley and Sons, New York) 1985.
Forsberg et al., Inorg. Chem. v. 8, pp. 883-888 (1969).
Morrison and Boyd, Organic Chemistry, 2d ed., Allyn and Bacon, Inc., Boston; pp. 751, 758, 759 (1969).
Degering, ed. Organic Chemistry, 6th ed., Barnes & Noble, Inc., New York, p. 144, (1962).
Gansow et al., Inorg. Chem. 25, 2772-2781 (1986).
Meares et al., Analytical Biochem. 142, 68-78 (1984).

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