Process for preparing [IR-(1.alpha.,2.beta.-3.alpha.)]-2-amino-9

Details Process for preparing [IR-(1.alpha.,2.beta.-3.alpha.)]-2-amino-9 Process for preparing [IR-(1.alpha.,2.beta.-3.alpha.)]-2-amino-9

1994-11-04

1996-05-14

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Pteroyl per se or having -c-, wherein x is chalcogen, bonded...

544266, C07D47318

Patent

active

055169031

ABSTRACT:
The protected cyclobutanone of the formula ##STR1## is treated with a dialkylaluminum chloride, an alkylaluminum dichloride, a trialkylaluminum compound, hydrogen in the presence of the catalysts ruthenium black or ruthenium on alumina, diphenyl-silane in the presence of tris(triphenylphosphine) rhodium (I) chloride, or iridium tetrachloride to yield the corresponding diprotected cyclobutanol. This compound is useful as an intermediate in the preparation of antiviral agents.

REFERENCES:
patent: 2936324 (1960-05-01), Haser et al.
patent: 5064961 (1991-11-01), Bisacchi et al.
patent: 5126345 (1992-06-01), Slusarchyk et al.
patent: 5153352 (1992-10-01), Norbek et al.
patent: 5185463 (1993-02-01), Godfrey et al.
patent: 5412134 (1995-05-01), Singh et al.
Fieser et al., "Reagents For Organic Synthesis", vol. 2, 1972, p. 228.
Fieser et al., "Reagnets For Organic Synthesis", vol. 9, 1981, p. 486.
Fieser et al., "Reagents For Organic Synthesis", vol. 6, 1977, p. 307.

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