Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1983-09-07
1985-09-17
Nucker, Christine M.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424 11, 424 9, A61K 4900, A61K 4300, C07J 300
Patent
active
045419574
ABSTRACT:
17.alpha.-[(E)-2-Iodovinyl]-estra-1,3,5(10)-triene-3,17.beta.-diol wherein the iodine atom is radioactive can be produced from (E)-[3-acyloxy-17.beta.-hydroxyestra-1,3,5(10)-triene-17.alpha.-yl]vinyl dihydroxyborane in an excellent yield by iodinating the same and hydrolyzing the resulting 3-acyloxy-17.alpha.-[(E)-2-iodovinyl]-estra-1,3,5(10)-triene-17.beta.-ol.
REFERENCES:
patent: 4450149 (1984-05-01), Kabalka et al.
Hanson et al., Abstr. Pap. Am. Chem. Soc., 182, (1981), NUCL 56.
Hanson et al., From Nuclear Medicine and Biology Advances, Ed. C. Raynaud, Pergamon Press, Oxford, pp. 3200-3203.
Kabalka et al., Chem. Abst., 98, (1983), #89725j.
Hanson et al., Chem. Abst., 97, (1982), #177890a.
Eckelman William
Nakatsuka Iwao
Rzeszotarski Waclaw J.
Nucker Christine M.
The George Washington University
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