Process for preparing insulin compounds

Details Process for preparing insulin compounds Process for preparing insulin compounds

2008-07-08

2008-07-08

Gupta, Anish (Department: 1654)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Insulin; related peptides

C530S333000, C530S338000

Reexamination Certificate

active

07396903

ABSTRACT:
A preferred way of converting insulin precursors into insulin compounds is to perform an enzymatic peptide cleavage in an aqueous medium and, thereafter, without removal of the intermediate product formed, to add an amino acid ester or a peptide ester and an organic solvent so that the desired coupling takes place.

REFERENCES:
patent: 4343898 (1982-08-01), Markussen
patent: 4579820 (1986-04-01), Breddam et al.
patent: 4601979 (1986-07-01), Andresen et al.
patent: 87238 (1983-08-01), None
patent: 0092829 (1983-11-01), None
patent: 83/00504 (1983-02-01), None

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