Process for preparing imidazopyridine derivatives

Details Process for preparing imidazopyridine derivatives Process for preparing imidazopyridine derivatives

1994-11-29

1996-03-12

Dentz, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D47104

Patent

active

054987156

ABSTRACT:
A process for preparing imidazopyridine derivatives of the general formula: ##STR1## wherein R.sub.1 is hydrogen or an alkyl group, and R.sub.2, R.sub.3 and R.sub.4 are identical or different and are hydrogen, an alkyl group, a cycloalkyl group, an aryl group, an aralkyl group or a halogen atom. In this process, a 2-amino-3-nitropyridine is hydrogenated in the presence of a hydrogenation catalyst and the hydrogenation product is condensed with a carboxylic acid simultaneously present in the reaction mixture to give the end product. The imidazopyridine derivatives are intermediates for the preparation of angiotensin II antagonists.

REFERENCES:
patent: 5240938 (1993-08-01), Greenlee et al.
Troschutz et al., Arch. Pharm., 325, (1992), pp. 785 to 789.
Horner et al., Ann. 579, pp. 204-211 (1953).
Fieser and Fieser, Advanced Org. Chem., Reinhold Pub., pp. 706-707 (1961).

Affiliated with

Also associated with

Rating

Process for preparing imidazopyridine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing imidazopyridine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing imidazopyridine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2100879