Process for preparing imidazopyran derivatives

Details Process for preparing imidazopyran derivatives Process for preparing imidazopyran derivatives

2006-10-03

2006-10-03

Habte, Kahsay (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

C548S327500

Reexamination Certificate

active

07115736

ABSTRACT:
A novel process for preparing imidazopyran derivatives of the formula:wherein R1is halogen atom, hydrogen atom, C1to C3alkyl group, aryl group, or aryl group substituted by C1to C3alkyl group, by using dinitroimidazole and 2,3-epoxy-1-propanol as starting materials and being followed by five steps.

REFERENCES:
patent: 6087358 (2000-07-01), Baker et al.
patent: 97/01562 (1997-01-01), None
Krysztof Walczak et al., “Synthesis of Acyclic Nitroazole Nucleosides and Their Incorporation into Oligonucleotides, and Their Duplex and Triplex Formulation”, Helvetica Chimica Acta, vol. 87, pp. 469-478, XP002354143, Feb. 2004.
Sanzhong Luo et al., “Ytterbium Triflate Catalyzed Reactions of Epoxide with Nitrogen Heterocycles Under Solvent-Free Condition”, Synthetic Communications, vol. 33, No. 17, pp. 2989-2994, XP009057051, 2003.
Kelvin K. Ogilvie et al., “A general method for selective silylation of primary hydroxy groups in carbohydrates and related compounds”, Carbohydrate Research, vol. 115, pp. 234-239, XP002354144, 1983.
Theodora W. Greene et al., “Protective Groups in Organic Synthesis”, John Wiley & Sons, Inc., pp. 86-119, XP002354152, 1991.

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