Process for preparing hepatitis A virus

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Inactivation or attenuation; producing viral subunits

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435235, 424 89, C12N 708

Patent

active

044120028

ABSTRACT:
Hepatitis A virus is harvested from persistently infected cells, the cells are then trypsinized, replanted and a second harvest of hepatitis A virus is obtained. The cells can be trypsinized and replanted and harvested indefinitely.

REFERENCES:
patent: 3948725 (1976-04-01), Irie
patent: 4164566 (1979-08-01), Provost et al.
Provost et al.-PSEBM, vol. 160 (1979), pp. 213-221.

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