Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1986-06-18
1988-06-07
Ford, John M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
546209, 548183, 548337, 549315, C07D23922, C07D40110, C07D23366, C07D30762
Patent
active
047497904
ABSTRACT:
H.sub.2 -receptor antagonist ascorbate compounds, derived from the lactone form of 3-ketohexuronic acid of Formula ##STR1## where (X) may be 1, 2 or 3 and (Y) may be 1 or 2, R.sub.1 and R.sub.2 are both hydrogen or R.sub.1 may be hydroxyl, R.sub.2 hydrogen or the O-alkylidene, 5,6-diacyl, 6-acyl derivatives thereof having two to sixteen carbon atoms, or a 6-phosphate, R.sub.3 being an organic base or a salt thereof having one or more basic functional groups, having H.sub.2 -receptor antagonist properties and capable of reacting with nitrous acid, and a process for the preparation of said compounds.
REFERENCES:
patent: 4251449 (1981-02-01), Schreur
Ballester-Rodes Montserrat
Palomo-Coll Antonio L.
Polamo-Nicolau Francisco E.
Barisintex, S.A
Ford John M.
Richter J.
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