Process for preparing guanine derivatives

Details Process for preparing guanine derivatives Process for preparing guanine derivatives

1987-10-14

1989-10-17

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen bonded directly to ring carbon of the purine ring...

544277, C07D47318, A61K 3152

Patent

active

048748625

ABSTRACT:
Novel guanine derivatives are described as agents for treating autoimmune diseases as well as a method of manufacture and pharmaceutical compositions thereof.

REFERENCES:
patent: 4579849 (1986-04-01), MacCoss et al.
R. E. Holmes, et al, "Purine Nucleosides. VII. Direct Bromination of Adenoisine, Deoxyadenosine, Guanosine, and Related Purine Nucleosides," (Nov. 12, 1963), pp. 1242-1245, vol. 86.
J. C. Sircar, et al, "Free-Radical Bromination of Methyl Abietate by N-Bromosuccinimide and Solvolysis of the Products," J. Org. Chem. 55, 3090-3093 (1970).
L. Horner et al, "N-Bromsuccinimide, Its Properties and Reactions The Course of Substitution," Newer Methods of Preparative Organic Chemistry, vol. III, pp. 151-188 (1964).

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