Process for preparing guanidine derivatives

Details Process for preparing guanidine derivatives Process for preparing guanidine derivatives

1999-12-13

2000-11-07

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C07C22926

Patent

active

061439290

ABSTRACT:
A process for preparing guanidine derivatives, in particular creatine, is described and entails an O-alkylisourea salt and a primary or secondary amine being reacted in the presence of crystals of a guanidine derivative.

REFERENCES:
patent: 5719319 (1998-02-01), Weiss et al.
Fearing et al. "Some Strongly Basic Derivatives of (+)- and (-)-1-Hydrosy-2-aminobutane.sup.1 " JACS, vol. 76, Sep. 5, 1954, pp. 4382-4385.
Schwetlick et la., "Organikum " 1977, VEB Deutscher Verlang der Wissenschaften XP-002133400 pp. 44-46.
Kirk-Othmer Encyclopedia of Chemical Technology, 4th ed., (1993), vol. 7, John Wiley & Sons, NY, pp. 692-695 and 721, 1993.

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