Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2009-04-16
2011-11-22
Bland, Layla (Department: 1623)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
Reexamination Certificate
active
08063202
ABSTRACT:
Glycopeptide having at least one asparagine-linked oligosaccharide at a desired position of the peptide chain obtained by:(1) esterifying hydroxyl of a resin and carboxyl of ah amino acid having amino group nitrogen protected with a fat-soluble protective group (AGFPG),(2) removing the protective group to form a free amino group,(3) amidating the free amino group and carboxyl of an amino acid having AGFPG,(4) removing the protective group,(5) repeating the steps (3) and (4),(6) amidating the free amino group and carboxyl of the asparagine portion of an asparagine-linked oligosaccharide having AGFPG,(7) removing the protective group,(8) amidating the free amino group and carboxyl of an amino acid having AGFPG,(9) repeating steps (7) and (8),(10) removing the protective group, and(11) cutting off the resin with an acid;glycopeptide obtained by transferring sialic acid or a derivative thereof to the above glycopeptide.
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Bland Layla
Osha • Liang LLP
Otsuka Chemical Co. Ltd.
Yasuhiro Kajihara
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