Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Peptides containing saccharide radicals – e.g. – bleomycins – etc.
Reexamination Certificate
2006-07-11
2006-07-11
Campell, Bruce R. (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Peptides containing saccharide radicals, e.g., bleomycins, etc.
Reexamination Certificate
active
07074890
ABSTRACT:
Disclosed are processes for preparing glycopeptide phosphonate derivatives having an amino-containing side chain. Several of the process steps are conducted in a single reaction vessel without isolation of intermediate reaction products, thereby generating less waste and improving the overall efficiency and yield of the process.
REFERENCES:
patent: 3160632 (1964-12-01), Toy et al.
patent: 4643987 (1987-02-01), Nagarajan et al.
patent: 4698327 (1987-10-01), Nagarajan et al.
patent: 5591714 (1997-01-01), Nagarajan et al.
patent: 5750509 (1998-05-01), Malabarba et al.
patent: 5840684 (1998-11-01), Cooper et al.
patent: 5916873 (1999-06-01), Cooper et al.
patent: 5952466 (1999-09-01), Berglund et al.
patent: 5998581 (1999-12-01), Berglund et al.
patent: 6392012 (2002-05-01), Judice et al.
patent: 6444786 (2002-09-01), Judice et al.
patent: 6455669 (2002-09-01), Judice et al.
patent: 6518242 (2003-02-01), Chen et al.
patent: 6635618 (2003-10-01), Leadbetter et al.
patent: 2002/0010131 (2002-01-01), Linsell
patent: 2002/0022590 (2002-02-01), Leadbetter et al.
patent: 2002/0049156 (2002-04-01), Yang et al.
patent: 0 201 251 (1986-12-01), None
patent: 0 376 041 (1990-07-01), None
patent: 0 525 499 (1993-02-01), None
patent: 0 667 353 (1995-08-01), None
patent: 0 816 378 (1998-01-01), None
patent: 0 873 997 (1998-10-01), None
patent: WO 98/21952 (1998-05-01), None
patent: WO 99/42476 (1999-08-01), None
patent: WO 00/39156 (2000-07-01), None
patent: WO 00/59528 (2000-10-01), None
patent: WO 01/82971 (2001-11-01), None
patent: WO 01/83521 (2001-11-01), None
patent: WO 01/98328 (2001-12-01), None
Cooper et al., “Reductive Alkylation of Glycopeptide Antibiotics:Synthesis and Antibacterial Activity”, The Journal of Antibiotics, vol. 49, No. 6, pp. 575-581 (1996).
Nagarajan et al., “Synthesis and Antibacterial Evaluation ofN-Alkyl Vancomycins”, The Journal of Antibiotics, vol. XLII, No. 1, pp. 63-72 (1988).
Nicolaou et al., “Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics”, Angew Chem. Int. Ed., vol. 38, No. 15, pp. 2097-2152 (1999).
Pavlov et al., “A New Type of Chemical Modification of Glycopeptides Antibiotics:Aminomethylated Derivatives of Eremomycin and Their Antibacterial Activity”, The Journal of Antibiotics, vol. 50, No. 6, pp. 509-513 (1997).
Pavlov et al., “Chemical Modification of Glycopeptide Antibiotics [VC1]”, Russian Journal of Bioorganic Chemistry, vol. 24, No. 9, pp. 570-587 (1998).
Rodriguez et al., “Novel Glycopeptide Antibiotics:N-Alkylated Derivatives Active Against Vancomycin-Resistant Enterococci”, The Journal of Antibiotics, vol. 51, No. 6, pp. 560-569 (1998).
Snyder et al., “Enzymatic Deacylation of Teicoplanin Followed by Reductive Alkylation: Synthesis and Antibacterial Activity of New Glycopeptides”, The Journal of Antibiotics, vol. 51, No. 10, pp. 945-951 (1998).
Leadbetter Michael R.
Lee Junning
Linsell Martin S.
Liu Jyanwei
Audet Maury
Campell Bruce R.
Hagenah Jeffrey A.
Theravance Inc.
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