Process for preparing extract from rhus verniciflua and...

Details Process for preparing extract from rhus verniciflua and... Process for preparing extract from rhus verniciflua and...

2005-09-08

2009-12-08

Hoffman, Susan C (Department: 1655)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

Reexamination Certificate

active

07629006

ABSTRACT:
The present invention provides a process for preparing an extract ofRhus vernicifluaby using water and organic solvents to extract active ingredients, which comprises (a) adding water or a mixture of water and alcohol as the solvent toRhus vernicifluato extract the soluble components, then filtering the resultant product to obtain a filtrate, and concentrating and drying the filtrate to obtain a solid fraction; (b) re-extracting the solid fraction obtained in the previous step with highly purified ethanol, then filtering the resultant product to obtain a filtrate, and concentrating and drying the filtrate to obtain a solid fraction; (c) adding a saturated hydrocarbon having 5 to 7 carbon atoms to the solid fraction obtained in the previous step to dissolve allergy-inducing components, and then removing the hydrocarbon to obtain a solid fraction; and (d) adding water to the solid fraction obtained in the previous step to extract water-soluble components. The extract obtained according to the process for preparing an extract ofRhus vernicifluaof the invention does not induce allergies, since toxic substances of lacquer are effectively removed, and various inherent active ingredients of lacquer can be extracted with high yield, compared with conventional processes.

REFERENCES:
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Coley et al. (Epidemiologic Reviews (2008), vol. 30, pp. 35-66).
Translation of KR 2001-0111159-2001.
Lim, K.T. et al. “Antioxidative effects of Ethanol extracts from Rhus Verniciflua Stokes (RVS) on mouse whole brain cells” In; Korean J. Food Sci. Technol. 1997;29(6):1248-54.
Kitts, et al. “Antitumorigenic and cytotoxic properties of an ethanol extract derived from Rhus Verniciflua Stokes (RVS)” In; J. Toxicol. Environ. Health A 2001; 64(4):357-71.

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