Process for preparing Estracyt compounds having a carcinostatic

Details Process for preparing Estracyt compounds having a carcinostatic Process for preparing Estracyt compounds having a carcinostatic

1985-03-01

1986-04-22

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07J 100

Patent

active

045841365

ABSTRACT:
An Estracyt compound having a carcinostatic bound thereto is obtained by reacting an Estracyt compound with a carcinostatic having one or more radicals selected from among COOH, Cl, NH.sub.2 and OH, either directly or after reaction with an amine to replace one or both Cl groups in the nitrogen mustard portion in the Estracyt compound with a NH.sub.2 group, in the presence or absence of a catalyst. The resulting compound is more effective in cancer control than the Estracyt compound associated substance.

REFERENCES:
patent: 4360663 (1982-11-01), Asano et al.

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