Process for preparing esters of 2-(6'-methoxy-2'-naphtyl)-propio

Details Process for preparing esters of 2-(6'-methoxy-2'-naphtyl)-propio Process for preparing esters of 2-(6'-methoxy-2'-naphtyl)-propio

1985-05-17

1986-09-02

Love, Ethel G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

C07C 4330

Patent

active

046097660

ABSTRACT:
Process for preparing esters of 2-(6'-methoxy-2'-naphtyl)-propionic acid via rearrangement of new ketals of 2-halo-1-(6'-methoxy-2'-naphtyl)-propan-1-one in the presence of a Lewis acid.
The esters thus obtained are useful as intermediate products for preparing Naproxen.
The process involves the preparation of the following new compounds:

REFERENCES:
patent: 3626012 (1971-12-01), Fried et al.
patent: 3935273 (1976-01-01), Fried et al.
patent: 4143064 (1979-03-01), Loeffler et al.

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