Process for preparing erythromycin derivative, such as roxithrom

Details Process for preparing erythromycin derivative, such as roxithrom Process for preparing erythromycin derivative, such as roxithrom

1999-02-19

2000-04-18

Peselev, Elli

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 72, 536 185, C07H 100, C07H 1708

Patent

active

06051695&

ABSTRACT:
A process for preparing an erythromycin derivative, such as roxithromycin, from the corresponding oxime is disclosed. The oxime is reacted with a metal alkoxide and results in improvements over prior art processes involving the oxime. Roxithromycin is a known anti-bacterial agent.

REFERENCES:
patent: 4349545 (1982-09-01), Gouin D'Ambrieres et al.
patent: 5808017 (1998-09-01), Chang

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