Process for preparing enantiomers of carbazole derivatives as 5-

Details Process for preparing enantiomers of carbazole derivatives as 5- Process for preparing enantiomers of carbazole derivatives as 5-

1997-01-06

1999-06-29

Ramsuer, Robert W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20988

Patent

active

059170549

ABSTRACT:
A (+) or (-) enantiomer of a compound of formula (I) wherein R.sup.4 is methyl or ethyl, or a salt, solvate or hydrate thereof, processes for preparing said compounds and pharmaceutical compositions containing them. Compounds of formula (+) are 5-HT.sub.1 -like agonists. ##STR1##

REFERENCES:
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patent: 5616603 (1997-04-01), Borrett et al.
patent: 5618947 (1997-04-01), Borrett et al.
patent: 5618948 (1997-04-01), Borrett et al.
patent: 5650426 (1997-07-01), Borrett et al.
U.S. application No. 08/969,903, King et al., filed Nov. 13, 1997.
U.S. application No. 08/442,720, King et al., filed May. 15, 1995.
Hacksell et al., "Chirality in drug research and design", Trends in Biotechnology, vol. 11, p. 73-74 (1993).
Ariens, "Nonchiral, homochiral and composite chiral drugs", Trends in Pharmacological Sciences, vol. 14, p. 68-75 (1993).

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