Process for preparing enantiomerically enriched...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

Reexamination Certificate

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C562S465000, C562S470000

Reexamination Certificate

active

11635302

ABSTRACT:
The present invention relates to a process for preparing enantiomerically enriched, optionally substituted 2-alkoxy-3-phenylpropionic acids by asymmetrically hydrogenating alkoxycinnamic acids.

REFERENCES:
patent: 3030359 (1962-04-01), Arens et al.
patent: 4239914 (1980-12-01), Campolmi et al.
patent: 5233084 (1993-08-01), Chan
patent: 2007/0142472 (2007-06-01), Yokozawa et al.
patent: 2001 261612 (2001-09-01), None
patent: WO 00/26200 (2000-05-01), None
patent: WO 01/11072 (2001-02-01), None
patent: 2005/051882 (2005-06-01), None
patent: WO 2005/051882 (2005-06-01), None
Linderberg et al. Organic Process Research & Development, 2004, vol. 8, pp. 838-845.
Nitta et al. Journal of Molecular Catalysis A: Chemical 212, 2004, pp. 155-159.
Yuriko Nitta. Bulletin of the Chemical Society of Japan, 2001, vol. 74, pp. 1971-1972.
Jones et al. Topics in Catalysis, 2003, vol. 25 (1-4), pp. 71-79.
Nitta et al. Bulletin of the Chemical Society of Japan, 2001, vol. 74, pp. 2161-2165.
Rouzaud et al. Helvetica Chimica Acta, 2003, vol. 86, pp. 1753-1759.
Burk et al. Journal of the American Chemical Society, 1998, vol. 10, pp. 4345-4353.
Lohray et al. Journal of Medicinal Chemistry, 2001, vol. 44, pp. 2675-2678.
Schmidt, Ulrich, et al.; “Synthesis and Enantioselective Hydrogenation of α-Acyloxyacrylates,”Synthesis, Nov. 1994, pp. 1138-1140.
Burk, Mark J., et al.; “Rh-DuPHOS-Catalyzed Enantioselective Hydrogenation of Enol Esters. Application to the Synthesis of Highly Enantioenriched α-Hydroxy Esters and 1,2-Diols,”J. Am. Chem. Soc., 1998, 120, pp. 4345-4353.
Lohray, Braj B., et al.; “(−)3-[4-[2-(Phenoxazin-10yl)ethoxy]phenyl]-2-ethoxypropanoic Acid [(−)DRF 2725]: A Dual PPAR Agonist with Potent Antihyperglycemic and Lipid Modulating Activity,”J. Med. Chem. 2001, 44, pp. 2675-2678.
Deussen, Heinz-Josef, et al.; “Process Development on the Enantioselective Enzymatic Hydrolysis ofS-Ethyl 2-Ethoxy-3-(4-hydroxyphenyl)propanoate,”Organic Process Research&Development, 2003, 7, pp. 82-88.
Tang, Wenjun, et al.; “New Chiral Phosphorus Ligands for Anantioselective Hydrogenation;”Chem. Rev.2003, 103, pp. 3029-2069.
Linderberg, Mats T.; “Claisen Condensation as a Facile Route to an α-Alkoxy-cinnamate: Synthesis of Ethyl (2S)-2-Ethoxy-3-(4-hydroxyphenyl)propanoate,”Organic Process Research&Development, 2004, 8, pp. 838-845.
P. E. Maligres et al., “Enantioselective Hydrogenation of α-Aryloxy α,β-Unsaturated Acids. Asymmetric Synthesis of α-Aryloxycarboxylic Acids”, Organic Letters, vol. 6, No. 18, pp. 3147-3150, 2004.

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