Process for preparing double stranded RNA

Details Process for preparing double stranded RNA Process for preparing double stranded RNA

1974-08-02

1976-06-29

Brown, Johnnie R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

195 15, 195 28N, 424 85, C07C 2102

Patent

active

039667073

ABSTRACT:
Virus particles capable of stimulating the production of interferon are isolated from fungal cells of the mould Aspergillus foetidus or Aspergillus niger or from the nutrient medium in which or on which Aspergillus foetidus or Aspergillus niger mould has been grown. Double-stranded RNA material can be isolated from the virus particles extracted from Aspergillus foetidus or Aspergillus niger and said RNA material is capable of stimulating production of interferon. Pharmaceutical compositions comprising said particles or said RNA material in combination with pharmaceutically acceptable carriers and excipients are also provided.

REFERENCES:
patent: 3597318 (1971-08-01), Sutherland et al.
patent: 3629235 (1971-12-01), Lampson et al.
Moyer et al., "Chem. Abst.", vol. 60, p. 10968(b), 1964.

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