Process for preparing diltiazem

Details Process for preparing diltiazem Process for preparing diltiazem

1997-07-07

1999-02-09

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549229, C07D31734, C07D32710

Patent

active

058696970

ABSTRACT:
A compound of formula (IV) ##STR1## wherein R.sup.1 is hydrogen, an alkyl, alkoxy, alkylamino, alkylthio, aryl, aryloxy, or halogen residue; R is an alkyl, or aryl residue, and X is S or C, which is a valuable intermediate for producing Diltiazem.

REFERENCES:
patent: 4663467 (1987-05-01), Kruper, Jr. et al.
patent: 5023342 (1991-06-01), Sharpless et al.
patent: 5272270 (1993-12-01), Hirsenkorn et al.
Carey, F. A. et al. Advanced Organic Chemistry Part A:Structure and Mechanisms (Plenum Press, N.Y.), pp. 258-261 (1990).
Solomons, T.W.G. Organic Chemistry (John Wiley & Sons, N.Y.), p. 242 (1992) .

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