Process for preparing dialkyl oxide metallocenes or diaryl...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heavy metal containing

Reexamination Certificate

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Reexamination Certificate

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08071802

ABSTRACT:
Process for preparing bridged, stereorigid, stereomerically pure dialkoxide metallocenes, diaryl oxide metallocenes and diphenoxide metallocenes of formula Q(Cp)(Cp′)M(OR3)2 in which Cp and Cp′ are independently cyclopentadienyl, indenyl or fluorenyl; Q is a bridge between Cp and Cp′; M is a group 4 transition metal, especially Zr, Hf or Ti; R3 is C1-C10 alkyl, optionally substituted by aryl groups, or optionally substituted C6-C10 aryl, characterized in that, a bridged, stereorigid metallocene dihalide Q(Cp)(Cp′)M(X)2, in the form of a rac/meso mixture, is reacted with an alkylating reagent R4-M-(X)n wherein R4 is C1-C10 alkyl or C6-C10 aryl; M is an alkali metal or alkaline earth metal; X is halogen; n is the oxidation number of M reduced by 1; and the resulting reaction mixture or isolated dialkylmetallocene is reacted with an alcohol, an aryl alcohol or a phenol of the general formula HO—R3.

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Habaue et al: “Optical resolution of chiral ethylenebis (4, 5, 6, 7-tethrahydro-1-idenyl) zirconium derivatives by high-performance liquid chromatography”; Chemistry Letters;, Jan. 1, 1996, pp. 383-384, XP002089633; ISSN: 036-7022; compound 4.
Fox S. et al: “Novel derivatives of ansa-titanocenes procured from 6-phenylfulvene: A combined experimental and theoretical study”; Inorganica Chimica Acta, vol. 357m No. 1; Jan. 1, 2004, pp. 225-234, XP009100296; ISSN: 0020-1693, paragraphs 02.4 and 02.9.
Search Report for International Application No. PCT/EP2008/001544 dated Sep. 9, 2008.

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