Process for preparing D-N-carbamoyl-.alpha.-amino acids

Details Process for preparing D-N-carbamoyl-.alpha.-amino acids Process for preparing D-N-carbamoyl-.alpha.-amino acids

1977-12-21

1980-12-02

Tanenholtz, Alvin F.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

435106, 435109, 435110, 435113, 435115, 435116, 435129, 435280, C12P 1302

Patent

active

042372275

ABSTRACT:
A process for preparing D-N-carbamoyl-.alpha.-amino acids by subjecting 5-substituted hydantoins to the action of a cultured broth, cells or treated cells of microorganisms having an ability in asymmetrically hydrolyzing the hydantoin ring in an aqueous medium of pH 7 to 10. The process is suited for the industrial manufacture of D-N-carbamoyl-.alpha.-amino acids which are useful intermediates for the preparation of medicines.

REFERENCES:
patent: 3320135 (1967-05-01), Okumura et al.
patent: 3494831 (1970-02-01), Nakayama et al.
patent: 4016037 (1977-04-01), Mitsugi et al.
patent: 4094741 (1978-06-01), Yamada et al.
patent: 4111749 (1978-09-01), Degen et al.
Journal of the Agricultural Chemical Society of Japan, vol. 43, No. 8, pp. 528-535 (1969).

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