Process for preparing conjugates consisting of a specific bindin

Details Process for preparing conjugates consisting of a specific bindin Process for preparing conjugates consisting of a specific bindin

1995-03-30

1996-07-09

Ceperley, Mary E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 5, 435 793, 435 795, 435188, 5303913, 5303915, G01N 33576, C12N 996

Patent

active

055344143

ABSTRACT:
The invention relates to a process for preparing conjugates consisting of a specific binding partner and a carbohydrate-containing protein, conjugates which can be prepared by this process and their use in enzyme immunoassays.

REFERENCES:
patent: 4002532 (1977-01-01), Weltman et al.
patent: 4587044 (1986-05-01), Miller et al.
patent: 5248772 (1993-09-01), Siiman et al.
"Immunoassay of Endogenous Plasma Insulin In Man", Rosalyn S. Yalow et al., J. Clin. Invest., 39:1157-1175 (1960).
"Enzyme-linked immunosorbent assay (ELISA) Quantitative assay of immuno-globulin G", Eva Engvall et al., Immunochemistry, 8(9-I):871-874 (1971).
"Immunoassay Using Antigen-Enzyme Conjugates", B. K. Van Weemen et al., FEBS-Letters, 15(3):232-236 (1971).
"Enzyme-Labeling of Antibodies and Their Fragments for Enzyme Immunoassay and Immunohistochemical Staining", Eiji Ishikawa et al., Journal of Immunoassay, 4(3):209-327 (1983).
"A Sandwich Enzyme Immunoassay of Rabbit Immunoglobulin G with an Enzyme Method and a New Solid Support", Hideaki Tanimori et. al., Journal of Immunological Methods, 62:123-131 (1983).
"Preparation of Protein Conjugates via Intermolecular Disulfide Bond Formation", Te Piao King et al., Biochemistry, 17(8):1499-1506 (1978).
"Preparation of enzyme-antibody or other enzyme-macromolecule conjugates", P. Tijssen, Laboratory Techniques in Biochemistry and Molecular Biology, pp. 221-278 (1985).
"Coupling of Enzymes to Proteins With Glutaraldehyde", Stratis Avrameas, Immunochemistry, 6:43-52 (1969).
Nakane, P and Kawaoi, A., "Peroxidase-Labeled Antibody: A New Method of Conjugation." The Journal of Histochemistry and Cytochemistry, vol. 22, No. 12, pp. 1084-1091, 1974.

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