Process for preparing cimetidine polymorph B

Details Process for preparing cimetidine polymorph B Process for preparing cimetidine polymorph B

1987-07-27

1988-11-22

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D23364

Patent

active

047867353

ABSTRACT:
A novel process for preparing cimetidine polymorph "B" comprises precipitating cimetidine from an aqueous-alcoholic solution of an acid addition salt. The precipitation is conducted at a temperature of above 15.degree. C.

REFERENCES:
B. Hegedus et al., Journal of Pharmaceutical & Biomedical Analysis, vol. 3, No. 4; pp. 303-313; 1985.

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