Process for preparing certain pyrrolotriazine compounds

Details Process for preparing certain pyrrolotriazine compounds Process for preparing certain pyrrolotriazine compounds

2005-08-23

2005-08-23

Balasubramanian, Venkataraman (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C548S452000

Reexamination Certificate

active

06933386

ABSTRACT:
The present invention relates to a process for preparing certain pyrrolotriazine compounds of the formulaand pharmaceutically acceptable salts thereof.The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

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