Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1979-05-31
1982-02-16
Chan, Nicky
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424283, C07D31158
Patent
active
043158625
ABSTRACT:
The preparation of cannabichromene (CBC) and homologues thereof by condensation of citral with a substituted resorcinol in the presence of a primary amine, and the use of these compounds to induce hypothermia and reduce inflammation in mammals, is disclosed. Preferably, the cannabichromene is administered as a novel composition, in combination with a pharmaceutically acceptable diluent carrier. A new compound 2-methyl-2(4-methyl-pent-3-enyl)-5-hydroxy-7-methylchromene (CBC-C.sub.1).
REFERENCES:
Kane et al., JACS, 90, 6551 (1968).
Crombie et al., J. Chem. Soc. (C), 796 (1971).
Crombie et al., J. Chem. Res. S (Synopses), 1977, (5), 114-115, (C.A. 87:102470s).
ElSohly Mahmoud A.
Turner Carlton E.
Chan Nicky
Stokes William D.
The University of Mississippi
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