Process for preparing branched ribonucleosides from...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S027200, C544S262000

Reexamination Certificate

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10544575

ABSTRACT:
A process is provided for the preparation of branched-chain ribonucleosides of formula (I):from the 1,2-anhydroderivatives of formula (II).wherein PG is a hydroxyl protecting group, B is a purine or pyrimidine nucleobase, and R1is C1-6alkyl. The compounds of formula (I) are inhibitors of HCV polymerase useful in the treatment of HCV infection.

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