Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2008-03-04
2008-03-04
Crane, L. E. (Department: 1623)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S027200, C544S262000
Reexamination Certificate
active
10544575
ABSTRACT:
A process is provided for the preparation of branched-chain ribonucleosides of formula (I):from the 1,2-anhydroderivatives of formula (II).wherein PG is a hydroxyl protecting group, B is a purine or pyrimidine nucleobase, and R1is C1-6alkyl. The compounds of formula (I) are inhibitors of HCV polymerase useful in the treatment of HCV infection.
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Bio Matthew M
Cowden Cameron
Petrillo Kimberly A.
Waters Marjorie See
Williams J. Michael
Crane L. E.
Durette Philippe L.
Heber Seldon O.
Merck & Co. , Inc.
Walton Kenneth R.
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