Process for preparing bleomycin group antibiotics

Details Process for preparing bleomycin group antibiotics Process for preparing bleomycin group antibiotics

1973-08-07

1976-04-27

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

H61K 3500

Patent

active

039535940

ABSTRACT:
This invention is concerned with the oxidative conversion of an unstable phleomycin group to a stable bleomycin group antibiotic having the partial structure: ##SPC1##
By treatment with potassium ferricyanide or manganese dioxide.

REFERENCES:
ikekawa et al., J. of Antibiotics, XVII-5, XVII-5, 1964, pp. 194-199.

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