Process for preparing biphenyltetrazole compounds

Details Process for preparing biphenyltetrazole compounds Process for preparing biphenyltetrazole compounds

1992-07-10

1994-05-10

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548250, 548254, C07D25704, C07D25706, C07D40306

Patent

active

053109287

ABSTRACT:
Method for the preparing biphenyltetrazole compounds which are angiotensin II receptor antagonists or which are useful intermediates to prepare angiotensin II receptor antagonists. An illustrative biphenyl tetrazole compound is 2-n-butyl-4-chloro-1-[(2'-(tetrazol-5-yl)-1,1'-biphenyl-4-yl)methyl]-1H-im idazole-5-methanol, potassium salt.

REFERENCES:
patent: 4820843 (1987-11-01), Aldrich et al.
patent: 5164518 (1992-11-01), Lavock
Bringmann et al., "The Directed Synthesis of Biaryl Compounds: Modern Concepts and Strategies", Angew. Chem. Int. Ed. Engl., vol. 29, 1990, pp. 977-991.
Duncia et al., "Three Synthetic Routes to a Sterically Hindered Tetrazole. A New One-Step Mild Conversion of an Amide into a Tetrazole", J. Org. Chem., 1991, 56, pp. 2395-2400.
Accounts of Chemical Research, vol. 15, No. 10, Oct. 1982, pp. 306-312, Washington, U.S., by P. Beak.

Affiliated with

Also associated with

Rating

Process for preparing biphenyltetrazole compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing biphenyltetrazole compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing biphenyltetrazole compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2413387