Process for preparing beta-ketoester compound

Details Process for preparing beta-ketoester compound Process for preparing beta-ketoester compound

2006-01-17

2006-01-17

Wilson, James O. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C546S310000, C546S315000

Reexamination Certificate

active

06987199

ABSTRACT:
The present invention relates to a new process for preparing beta-ketoester compound of the following formula (1), which is a useful intermediate for the synthesis of such quinoline antibiotics as Ciprofloxacin, Levofloxacin, Gemifloxacin, Trovafloxacin, etc. The quinoline antibiotics obtained from the above compound of formula (1) show potent antibacterial activity, and so are advantageously used as a therapeutic agent for bacterial infections of humans or animals.

REFERENCES:
patent: 5204478 (1993-04-01), Jennings
patent: 5380860 (1995-01-01), Busch et al.
patent: 3508816 (1986-07-01), None
patent: 333020 (1989-09-01), None
patent: 1019980047902 (1998-09-01), None
Hcaplus 107:77632, “Pyridinyl ketone derivatived”, Miyamoto et. al., Apr. 14, 1986.

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