Process for preparing benzylpyruvic acids and esters

Details Process for preparing benzylpyruvic acids and esters Process for preparing benzylpyruvic acids and esters

1989-03-09

1990-09-11

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560023, 560053, 562434, 562459, 562463, 558414, C07C 6976

Patent

active

049564900

ABSTRACT:
There is disclosed a continuous, non-isolation process for preparing benzylpyruvic acids and benzylpyruvic esters. The benzylpyruvic acids and esters obtained are useful as intermediates to prepare carboxyalkyl dipeptide compounds which are used as angiotension converting enzyme (ACE) inhibitors to treat hypertension.

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T. W. Russel, et al., J. Org. Chem., 42, No. 3 (1977).
S. Kim, et al., J. Org. Chem., 50, No. 5, 560-565 (1985).

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